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AZD 3043  (Synonyms: THRX 918661)

目录号: HY-108204
产品使用指南

AZD 3043 (THRX 918661) 是一种GABA(A)受体的正变构调节剂,具有镇静催眠活性。AZD 3043在体外可增强GABA(A)受体介导的氯离子电流,在体内可产生催眠和脑电图抑制作用,且由于其酯酶依赖的代谢途径,作用时间短,即使长时间输注也能快速清除,可能具有临床应用潜力。

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AZD 3043 Chemical Structure

AZD 3043 Chemical Structure

CAS No. : 579494-66-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZD 3043 (THRX 918661) is a positive allosteric modulator of GABA(A) receptors with sedative and hypnotic activity. AZD 3043 can enhance GABA(A) receptor-mediated chloride currents in vitro and produce hypnotic and electroencephalographic inhibitory effects in vivo. Due to its esterase-dependent metabolic pathway, it has a short duration of action and can be quickly cleared even after long-term infusion, which may have clinical application potential.

分子量

351.44

Formula

C19H29NO5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

AZD 3043 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AZD 3043
目录号:
HY-108204
需求量: