2. Metabolic Enzyme/Protease
  3. Phosphorylase
  4. BAY R3401

BAY R3401 是一种口服有效的糖原磷酸化酶 (glycogen phosphorylase) 抑制剂，可实现对肝糖原分解的不可逆和非选择性抑制。BAY R3401 抑制肝细胞中的糖原分解，在 HL-7702 和 HepG2 细胞中的 IC50 值分别为 27.06 和 52.83 μM。BAY R3401 可用于 2 型糖尿病的研究。

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BAY R3401 Chemical Structure

BAY R3401 Chemical Structure

CAS No. : 100276-03-7

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BAY R3401 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BAY R3401 is an orally active glycogen phosphorylase inhibitor that can achieve irreversible and non-selective inhibition of hepatic glycogenolysis. BAY R3401 inhibits glycogenolysis in liver cells, with IC50 values of 27.06 and 52.83 μM in HL-7702 and HepG2 cells, respectively. BAY R3401 can be used for the research of type 2 diabetes[1].

分子量

375.85

Formula

C20H22ClNO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BAY R3401 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BAY R3401100276-03-7BAY R 3401BAY R-3401PhosphorylaseHL-7702HepG2liver cellshepatic glycogenolysisInhibitorinhibitorinhibit

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