1. Metabolic Enzyme/Protease Anti-infection
  2. Glutathione S-transferase Bacterial
  3. Benastatin B

Benastatin B 是谷胱甘肽 S-转移酶 (glutathione S-transferase) 抑制剂,可以抑制人 pi GSTIC50 为 1.10 μg/mL。Benastatin B 具有广谱抗菌功效,可抑制 MRSA,MIC 为 3.1 μg/mL。Benastatin B 通过抑制 IgE 介导的 β-己糖胺酶 (β-hexosaminidase) 释放而发挥抗炎活性,IC50 为 79 μg/mL。

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Benastatin B Chemical Structure

Benastatin B Chemical Structure

CAS No. : 138968-86-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC50 of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC50 of 79 μg/mL[1][2].

分子量

502.56

Formula

C30H30O7

CAS 号
结构分类
初始来源

Streptomyces sp. MI384-DF12

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Benastatin B
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HY-N12261
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