2. 生化试剂
  3. 细胞实验试剂
  4. Betamethasone 17-Propionate

Betamethasone 17-Propionate  (Synonyms: 倍他米松17-丙酸酯)

目录号: HY-W342458
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Betamethasone 17-Propionate 是一种用于研究对大鼠内毒素诱导葡萄膜炎作用的化合物，具有在一定剂量下通过滴眼和全身给药可抑制内毒素诱导的葡萄膜炎中细胞渗入房水的活性。但相比其他一些化合物，其抑制效果相对较弱。同时，全身给药时剂量为 1mg/kg。此外，Betamethasone 17-Propionate 在体外白细胞介素 -8（IL -8）释放试验中，其对大鼠腹膜渗出细胞释放 IL -8 的抑制作用弱于倍他米松。并且，倍他米松二丙酸酯与 Betamethasone 17-Propionate 同时添加会降低倍他米松对细胞浸润和 IL -1β基因表达的抑制作用。

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Betamethasone 17-Propionate Chemical Structure

Betamethasone 17-Propionate Chemical Structure

CAS No. : 5534-13-4

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Betamethasone 17-Propionate 相关抗体

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  • 生物活性

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生物活性

Betamethasone 17-Propionate is a compound used to study its effects on endotoxin-induced uveitis in rats. It has the activity of inhibiting the infiltration of cells into the aqueous humor in endotoxin-induced uveitis by eye drops and systemic administration at a certain dose. However, its inhibitory effect is relatively weak compared with some other compounds. At the same time, the dose for systemic administration is 1mg/kg. In addition, Betamethasone 17-Propionate has a weaker inhibitory effect on the release of IL-8 from rat peritoneal exudate cells in an in vitro interleukin-8 (IL-8) release assay than betamethasone. Moreover, the simultaneous addition of betamethasone dipropionate and betamethasone 17-Propionate reduces the inhibitory effect of betamethasone on cell infiltration and IL-1β gene expression.

分子量

448.52

Formula

C25H33FO6
CAS 号
中文名称

17-丙酸倍他米松； 倍他米松17-丙酸酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Betamethasone 17-Propionate 相关分类

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Keywords:

Betamethasone 17-Propionate5534-13-417-丙酸倍他米松 倍他米松17-丙酸酯OthersInhibitorinhibitorinhibit

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