2. Immunology/Inflammation
  3. IRAK Toll-like Receptor (TLR)
  4. BI1543673

BI1543673 是一种白细胞介素-1 受体相关激酶 4 (IRAK4) 抑制剂。BI1543673 可以减少人肺组织中 TLR4 和 TLR7/8 刺激的炎症反应。BI1543673 可以在 LPS 诱导的小鼠肺部炎症模型减少炎症信号传导。

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BI1543673 Chemical Structure

BI1543673 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

BI1543673 相关抗体

Top Publications Citing Use of Products

查看 IRAK 亚型特异性产品:

查看所有亚型
IRAK1 IRAK4

查看 Toll-like Receptor (TLR) 亚型特异性产品:

查看所有亚型
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BI1543673 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor. BI1543673 can reduce the inflammatory response stimulated by TLR4 and TLR7/8 in human lung tissue. BI1543673 can decrease inflammatory signaling in a mouse model of lung inflammation induced by LPS[1].
IC50 & Target

TLR4

 

TLR7

 

TLR8

 

分子量

515.65

Formula

C29H37N7O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BI1543673 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BI1543673BI 1543673BI-1543673IRAKToll-like Receptor (TLR)Interleukin-1 receptor associated kinaseIL-1R associated kinaseIRAK4TLR4TLR7/8lung inflammationInhibitorinhibitorinhibit

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产品名称：
BI1543673
目录号：
HY-169057
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