1. Anti-infection
  2. Bacterial
  3. Bio-AMS TFA

Bio-AMS (TFA) 是一种有效的细菌生物素蛋白连接酶 (biotin protein ligase) 抑制剂。Bio-AMS (TFA) 可选择性地抑制结核分枝杆菌 (Mtb),并抑制脂肪酸和脂类生物合成。

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Bio-AMS TFA Chemical Structure

Bio-AMS TFA Chemical Structure

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规格 价格 是否有货 数量
1 mg ¥1850
In-stock
5 mg ¥5500
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Other Forms of Bio-AMS TFA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Bio-AMS (TFA) is a potent bacterial biotin protein ligase inhibitor. Bio-AMS (TFA) possesses selective activity against Mycobacterium tuberculosis (Mtb) and arrests fatty acid and lipid biosynthesis[1].

IC50 & Target

Biotin protein ligase[1]

体外研究
(In Vitro)

Bio-AMS possesses excellent antitubercular activity against Mtb H37Rv and MDR/XDR-TB strains with MICs ranging from 0.16 to 0.625 μM and is not affected by changes to the primary carbon source[1].
Bio-AMS (2.5, 5 and 10 μM; 24 h) inhibits growth of Mtb in a concentration-dependent manner in Mtb-infected mouse macrophages; shows no signs of mitochondrial toxicity[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

685.65

Formula

C22H30F3N9O9S2

性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

参考文献

Bio-AMS TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bio-AMS TFA
目录号:
HY-115448A
需求量: