2. PROTAC
  3. PROTAC Linkers
  4. Boc-bipiperidine-ethynylbenzoic acid

Boc-bipiperidine-ethynylbenzoic acid 

目录号: HY-139661 纯度: 99.19%
COA 产品使用指南

摩尔计算器

Boc-bipiperidine-ethynylbenzoic acid 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子 ARD-61。

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Boc-bipiperidine-ethynylbenzoic acid Chemical Structure

Boc-bipiperidine-ethynylbenzoic acid Chemical Structure

CAS No. : 2308497-81-4

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Boc-bipiperidine-ethynylbenzoic acid 相关抗体

Top Publications Citing Use of Products

查看 PROTAC Linkers 亚型特异性产品:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61[1]. Boc-bipiperidine-ethynylbenzoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC50 & Target[1]

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-bipiperidine-ethynylbenzoic acid 相关抗体:
分子量

412.52

Formula

C24H32N2O4
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Boc-bipiperidine-ethynylbenzoic acid 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-bipiperidine-ethynylbenzoic acid2308497-81-4PROTAC LinkersAlkyletherARD-61PROTAClinkerInhibitorinhibitorinhibit

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Boc-bipiperidine-ethynylbenzoic acid
目录号：
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