2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Boc-NH-PEG4-CH2CH2NH2

Boc-NH-PEG4-CH2CH2NH2 

目录号: HY-W008352 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Boc-NH-PEG4-CH2CH2NH2 是一种可降解 (cleavable) 的 5 单元 PEG 类 ADC linker，用于抗体偶联活性分子 (ADC) 的合成。Boc-NH-PEG4-CH2CH2NH2 也是一种基于 PEG 的 PROTAC linker，可用于 PROTAC 的合成。

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Boc-NH-PEG4-CH2CH2NH2 Chemical Structure

Boc-NH-PEG4-CH2CH2NH2 Chemical Structure

CAS No. : 811442-84-9

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规格 价格 是否有货 数量
100 mg ￥100
In-stock
500 mg ￥220
In-stock
1 g ￥332
In-stock
5 g ￥1560
In-stock
10 g   询价  
50 g   询价  

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Customer Review

Boc-NH-PEG4-CH2CH2NH2 相关抗体

Top Publications Citing Use of Products

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查看所有亚型
PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-NH-PEG4-CH2CH2NH2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Cleavable Linker

 

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-NH-PEG4-CH2CH2NH2 相关抗体:
分子量

336.42

Formula

C15H32N2O6
CAS 号
性状

液体（密度：1.059 g/cm3）

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

COA (278 KB) HNMR (120 KB)

产品使用指南 (1538 KB)
参考文献

Boc-NH-PEG4-CH2CH2NH2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-NH-PEG4-CH2CH2NH2811442-84-9ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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产品名称：
Boc-NH-PEG4-CH2CH2NH2
目录号：
HY-W008352
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