1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. Bradanicline hydrochloride

Bradanicline hydrochloride  (Synonyms: TC-5619 hydrochloride)

目录号: HY-18060A
产品使用指南

Bradanicline hydrochloride (TC-5619 hydrochloride) 是 Bradanicline (HY-18060) 的盐酸盐形式。Bradanicline hydrochloride 是 α7 烟碱乙酰胆碱受体 (nAChR) 的选择性激动剂,对人 α7 nAChREC50 为 17 nM,Ki 为 1.4 nM。Bradanicline hydrochloride 可以于研究认知障碍和精神分裂症。

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Bradanicline hydrochloride Chemical Structure

Bradanicline hydrochloride Chemical Structure

CAS No. : 1111941-90-2

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Bradanicline hydrochloride 的其他形式现货产品:

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  • 纯度 & 产品资料

  • 参考文献

生物活性

Bradanicline hydrochloride (TC-5619 hydrochloride) is the hydrochloride salt form of Bradanicline (HY-18060). Bradanicline hydrochloride is a selective agonist for α7 nicotinic acetylcholine receptor (nAChR), with EC50 of 17 nM for human α7 nAChR and Ki of 1.4 nM. Bradanicline hydrochloride is used for the research of cognitive disorders and schizophrenia[1][2].

IC50 & Target

EC50: 17 nM (human α7 nAChR) Ki: 1.4 nM (human α7 nAChR)

分子量

397.90

Formula

C22H24ClN3O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Bradanicline hydrochloride
目录号:
HY-18060A
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