2. Anti-infection
  3. Enterovirus Virus Protease
  4. BTA-188

BTA-188 是一种哒嗪基肟醚，是具有口服活性的，有效的鼻病毒 (HRV) 和肠道病毒 (EV) 71 抑制剂。BTA-188 抑制 HRV-2 复制，IC50 为 0.8 nM，IC90 为 11 nM。BTA-188 抑制肠道病毒，IC50 为 82，IC90 为 109 nM。BTA-188 是一种潜在的化疗剂，有潜力用于小核糖核酸病毒科病毒引起的感染的研究。

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BTA-188 Chemical Structure

BTA-188 Chemical Structure

CAS No. : 314062-80-1

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BTA-188 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

BTA-188, a pyridazinyl oxime ether, is an orally active, potent inhibitor of rhinoviruses (HRV) and enterovirus (EV) 71 in vitro. BTA-188 inhibits HRV-2 replication with an IC50 of 0.8 nM and an IC90 of 11 nM. BTA-188 inhibits enterovirus with an IC50 of 82 and an IC90 of 109 nM. BTA-188 is a potential chemotherapeutic agent for infections caused by the viruses in the Picornaviridae[1].

分子量

368.47

Formula

C21H28N4O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BTA-188 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BTA-188314062-80-1BTA188BTA 188EnterovirusVirus ProteaseRhinovirusHRVHRVsHEVHEVspyridazinyl oxime etherorallyrhinovirusesenterovirusEVHRV-2chemotherapeuticPicornaviridaeInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-162022
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