2. TGF-beta/Smad
  3. TGF-β Receptor
  4. BUR1

BUR1 是一种 BMP 上调剂 (EC50: 98 nM) 并激活 BMPRII 信号传导。BUR1 诱导 BMP2 和 PTGS2 表达。 BUR1 逆转野百合碱 (HY-N0750) 诱导大鼠的肺动脉高压。

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BUR1 Chemical Structure

BUR1 Chemical Structure

CAS No. : 23000-46-6

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规格 价格 是否有货 数量
1 mg ￥2240
In-stock
5 mg ￥5040
In-stock
10 mg 现货 询价
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100 mg   询价  

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Customer Review

BUR1 相关抗体

Top Publications Citing Use of Products

查看 TGF-β Receptor 亚型特异性产品:

查看所有亚型
ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BUR1 is a BMP upregulator (EC50: 98 nM) and activates BMPRII signalling. BUR1 induces BMP2 and PTGS2 expression. BUR1 reversed pulmonary arterial pressure in Monocrotaline (HY-N0750) induced rats[1].

体外研究
(In Vitro)

BUR1 (0.2 μM，15 分钟至 24 小时) 可增加 PAEC 中 DNA 结合抑制剂 1 (Id1) 的表达和 Smad1/5 的磷酸化[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BUR1 相关抗体:
体内研究
(In Vivo)

BUR1 (4.5 mg/天，灌胃， 3 周) 可逆转野百合碱 诱导的大鼠肺动脉压和右心室收缩压[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

279.34

Formula

C16H17N5
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

BUR1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BUR123000-46-6BUR 1BUR-1TGF-β ReceptorTransforming growth factor beta receptorspulmonary arterial pressurePAHMCTInhibitorinhibitorinhibit

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产品名称：
BUR1
目录号：
HY-121025
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