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  3. C20 Sphingomyelin (d18:1/20:0)

C20 Sphingomyelin (d18:1/20:0)  (Synonyms: N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))

目录号: HY-145549
产品使用指南

C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))是一种天然存在的鞘脂。在链脲佐菌素 (HY-13753) 诱发的糖尿病大鼠的海马体中,以及在人类血浆中,C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))的水平上调,与肥胖人类的胰岛素抵抗呈正相关。C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))在尼曼-匹克 C1 型疾病(一种神经退行性胆固醇鞘脂溶酶体贮积症)小鼠模型的肝脏中也上调。前列腺癌患者的血浆 C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM(d18:1/20:0))浓度降低。由于本产品来自天然来源,鞘脂骨架可能存在变异。

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C20 Sphingomyelin (d18:1/20:0) Chemical Structure

C20 Sphingomyelin (d18:1/20:0) Chemical Structure

CAS No. : 121999-68-6

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规格 价格 是否有货 数量
500 μg ¥7950
3 - 4 周

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin (HY-13753) and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer. As this product is derived from a natural source, there may be variations in the sphingoid backbone.

分子量

759.13

Formula

C43H87N2O6P

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

C20 Sphingomyelin (d18:1/20:0) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
C20 Sphingomyelin (d18:1/20:0)
目录号:
HY-145549
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