2. Metabolic Enzyme/Protease Apoptosis Stem Cell/Wnt MAPK/ERK Pathway
  3. Phosphatase Apoptosis ERK p38 MAPK JNK
  4. Cantharidic acid

Cantharidic acid  (Synonyms: 斑蝥酸)

目录号: HY-137135
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摩尔计算器

Cantharidic acid 是蛋白磷酸酶 2 (PP2A) 和蛋白磷酸酶 1 (PP1) 的选择性抑制剂。Cantharidic acid 通过上调 ERK1/2、p38 和 JNK1/2 通路抑制细胞活力，在亚 G1 期阻滞细胞周期，诱导 NPC-39 和 HONE-1 细胞凋亡 (apoptosis)。

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Cantharidic acid Chemical Structure

Cantharidic acid Chemical Structure

CAS No. : 28874-45-5

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Other Forms of Cantharidic acid:

Cantharidic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cantharidic acid is a selective inhibitor for protein phosphatase 2 (PP2A) and protein phosphatase 1 (PP1). Cantharidic acid inhibits cell viability and arrest cell cycle at sub G1 phase, induces apoptosis in cells NPC-39 and HONE-1 through the upregulation of ERK1/2, p38, and JNK1/2 pathway[1].

分子量

214.22

Formula

C10H14O5
CAS 号
中文名称

斑蝥酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cantharidic acid 相关分类

  • 摩尔计算器

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Keywords:

Cantharidic acid28874-45-5斑蝥酸PhosphataseApoptosisERKp38 MAPKJNKExtracellular signal regulated kinasesc-Jun N-terminal kinaseNPC-39NPC-BMHONE-1nasopharyngeal carcinomaNPCInhibitorinhibitorinhibit

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