2. Cell Cycle/DNA Damage
  3. CRISPR/Cas9
  4. Cas9-IN-2

Cas9-IN-2 是一种有效的 Cas9 抑制剂 (IC50=246 μM)，通过与 apo-Cas9 结合来防止 Cas9:gRNA 复合物的形成，可应用于调节和控制 Cas9 的活性。

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Cas9-IN-2 Chemical Structure

Cas9-IN-2 Chemical Structure

CAS No. : 1030133-34-6

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Cas9-IN-2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cas9-IN-2 is a potent Cas9 inhibitor (IC50=246 μM), Cas9-IN-2 acts by binding to apo-Cas9 to prevent Cas9:gRNA complex formation, which can potentially be applied to modulate and control Cas9 activity in various applications[1].

体外研究
(In Vitro)

Cas9-IN-1 (compound 2) (200 and 500 μM; overnight) helps the E. coli selection strain to survive SpyCas9-induced killing[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cas9-IN-2 相关抗体:
分子量

477.60

Formula

C21H27N5O4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cas9-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cas9-IN-21030133-34-6CRISPR/Cas9Cas9:gRNA complex formationapo-Cas9gRNAInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-144119
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