2. Anti-infection
  3. Antibiotic Fungal Bacterial
  4. Caspofungin

Caspofungin  (Synonyms: 卡泊芬苷; MK-0991; L-743872)

目录号: HY-17006A
产品使用指南

摩尔计算器

Caspofungin 是一种有效的抗真菌剂。Caspofungin 抑制真菌细胞壁成分 1,3-β-D 葡聚糖合酶的合成。

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Caspofungin Chemical Structure

Caspofungin Chemical Structure

CAS No. : 162808-62-0

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Caspofungin 的其他形式现货产品:

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Caspofungin 相关抗体

Top Publications Citing Use of Products

    Caspofungin purchased from MCE. Usage Cited in: Cell Physiol Biochem. 2016 Aug 12;39(3):939-949.  [Abstract]

    Arithmetic means±SEM (n=21) of erythrocyte annexin-V-binding following incubation for 48 hours to Ringer solution without (white bar) or with (black bars) Caspofungin (30-60 µg/mL).

    查看 Antibiotic 亚型特异性产品:

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    Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2].

    体内研究
    (In Vivo)

    Caspofungin (1-8 mg/kg; i.p.; daily, for 7 days) is able to penetrate the CNS in mice and achieve concentrations that result in the reduction of Candida burden in the brain[1].
    Caspofungin (0.41-41 μM; i.p.; for 5 weeks; male C57BL/6 mice) is a safe antifungal agent at vitreal concentrations of 0.41 to 4.1 μM in mice[2].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Complement component 5-deficient DBA/2N mice[1]
    Dosage: 1, 2, 4 and 8 mg/kg
    Administration: Intraperitoneal injection; daily, for 7 days.
    Result: Reduced the concentration of Candida load in the brain.
    Animal Model: Male C57BL/6 mice[2]
    Dosage: 0.41, 1.2, 2.5, 4.1, and 41 μM
    Administration: Intraperitoneal injection; for 5 weeks
    Result: Had nonsignificant alterations in their ERG waveforms from 0.41 to 4.1 μM.
    Clinical Trial
    分子量

    1093.31

    Formula

    C52H88N10O15
    CAS 号
    中文名称

    卡泊芬苷
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Caspofungin 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    质量   浓度   体积   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Caspofungin162808-62-0MK-0991 L-743872卡泊芬苷MK0991MK 0991L743872L 743872L-743872AntibioticFungalBacterialantifungalfungal cell wallβ-(l,3)-D-glucanInhibitorinhibitorinhibit

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