2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. Cav 3.1 blocker 1

Cav 3.1 blocker 1 (compound 12) 是一种 T 型钙通道 (T-type calcium channel) 阻滞剂，对 Cav3.1 的 IC50 值为 160 nM。Cav 3.1 blocker 1 对 Cav 3.2 有较弱的抑制作用 (IC50 为 5000 nM)，对 Cav 3.3 和 Cav 1.2 没有抑制作用 (IC50 >10000 nM)。

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Cav 3.1 blocker 1 Chemical Structure

Cav 3.1 blocker 1 Chemical Structure

CAS No. : 2158201-04-6

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Cav 3.1 blocker 1 相关抗体

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

  • 生物活性

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生物活性

Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel blocker with an IC50value of 160 nM for Cav3.1. Cav 3.1 blocker 1 weakly inhibits Cav 3.2 (IC50 of 5000 nM), and shows no inhibition on Cav 3.3 and Cav 1.2 (IC50 of >10000 nM)[1].

IC50 & Target[1]

CaV3.1

160 nM (IC50)

Cav3.2

5000 nM (IC50)

CaV3.3

>10000 nM (IC50)

CaV 1.2

>10000 nM (IC50)

分子量

519.44

Formula

C26H19F6N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cav 3.1 blocker 1 相关分类

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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  • Do most proteins show cross-species activity?

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Keywords:

Cav 3.1 blocker 12158201-04-6Calcium ChannelCa2+ channelsCa channelsCav 3.1 blockerInhibitorinhibitorinhibit

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