2. GPCR/G Protein
  3. Leukotriene Receptor
  4. CAY10583

CAY10583 是一种有效的、选择性的全白三烯 B4 受体 2 型 (BLT2) 激动剂。CAY10583 在体外直接促进角质形成细胞迁移 ，可加速伤口愈合。CAY10583 有潜力用于糖尿病创面活性分子的研究。

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CAY10583 Chemical Structure

CAY10583 Chemical Structure

CAS No. : 862891-27-8

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规格 价格 是否有货 数量
5 mg ￥1278
3 - 4 周
10 mg   询价  
50 mg   询价  

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CAY10583 相关抗体

Top Publications Citing Use of Products

查看 Leukotriene Receptor 亚型特异性产品:

查看所有亚型
LTB4 LTC4/CysLT2 LTD4/CysLT1 LTE4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAY10583 is a potent and selective full Leukotriene B4 receptor type 2 (BLT2) agonist. CAY10583 directly promotes keratinocyte migration in vitro and accelerates wound closure in vivo. CAY10583 is a promising pharmaceutical agent for diabetic wounds[1].

IC50 & Target[1]

BLT2

 

体外研究
(In Vitro)

CAY10583 (1 nM-1μM; 24 hours) promotes wound closure via keratinocyte migration. And CAY10583 has no significant effect of on keratinocyte proliferation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAY10583 相关抗体:
体内研究
(In Vivo)

CAY10583 (administered topically to full-thickness wounds; 10 μM; 14 days) significantly results in a greater wound closure than the control group. The difference in wound closure between the CAY-treated group and the control group is pronounced over time until day 10. And the difference is approximately 6% at day 4 and reaches almost 20% at day 8. Notably, 100% closure was observed in the CAY-treated group at day 14[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Lewis rats (6-9 weeks of age, 180-220 g)[1]
Dosage: 10 μM; 14 days
Administration: Administered topically to full-thickness wounds; 10 μM; 14 days
Result: Accelerated in vivo wound healing by topical application.
分子量

387.47

Formula

C25H25NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAY10583 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAY10583862891-27-8CAY 10583CAY-10583Leukotriene ReceptorDiabetewound healingleukotriene B4 receptor type 2keratinocytefibroblastInhibitorinhibitorinhibit

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产品名称：
CAY10583
目录号：
HY-122124
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