2. Cell Cycle/DNA Damage Apoptosis
  3. Topoisomerase DNA/RNA Synthesis Apoptosis Necroptosis
  4. Cholesterol hemisuccinate Tris salt

Cholesterol hemisuccinate Tris salt  (Synonyms: Cholesterol hydrogen succinate Tris salt; CHS-Tris)

目录号: HY-W010800A
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Cholesterol hemisuccinate Tris salt (CHS-Tris) 是一种具有保肝和抗癌活性的物质。Cholesterol hemisuccinate Tris salt 抑制对乙酰氨基酚 (AAP, HY-66005) 的肝毒性，并防止 AAP 诱导的肝细胞凋亡 (apoptosis) 和坏死 (necrosis)。Cholesterol hemisuccinate Tris salt 抑制 DNA 聚合酶 (DNA polymerase) 和 DNA 拓扑异构酶 (DNA topoisomerase)，从而抑制 DNA 复制和修复以及细胞分裂。因此，胆固醇半琥珀酸酯抑制肿瘤生长。

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Cholesterol hemisuccinate Tris salt Chemical Structure

Cholesterol hemisuccinate Tris salt Chemical Structure

CAS No. : 102601-49-0

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Cholesterol hemisuccinate Tris salt 的其他形式现货产品:

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Cholesterol hemisuccinate Tris salt 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cholesterol hemisuccinate Tris salt (CHS-Tris) is a with hepatoprotective an anticancer activity. Cholesterol hemisuccinate Tris salt inhibits Acetaminophen (AAP, HY-66005) hepatotoxicity, and prevents AAP-induced hepatic apoptosis and necrosis. Cholesterol hemisuccinate Tris salt inhibits DNA polymerase and DNA topoisomerase to inhibit DNA replication and repair and cell division. Thus, Cholesterol hemisuccinate Tris salt inhibits tumor growth[1][2].

分子量

607.86

Formula

C35H61NO7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cholesterol hemisuccinate Tris salt 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cholesterol hemisuccinate102601-49-0Cholesterol hydrogen succinate CHS-TrisTopoisomeraseDNA/RNA SynthesisApoptosisNecroptosisInhibitorinhibitorinhibit

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