cis-Trismethoxy resveratrol (Synonyms: (Z)-3,5,4'-Trimethoxystilbene)

目录号: HY-121989 纯度: ≥98.0%: FAQs
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Cis-trismethoxy resveratrol 是一种有效的抗有丝分裂活性物，抑制微管蛋白聚合，IC₅₀ 值为 4 μM。

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cis-Trismethoxy resveratrol Chemical Structure

CAS No. : 94608-23-8

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规格	价格	是否有货	数量
5 mg (184.97 mM * 100 μL in Ethanol)	￥270	In-stock
10 mg (184.97 mM * 200 μL in Ethanol)	￥405	In-stock

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参考文献

生物活性

Cis-trismethoxy resveratrol is a potent anti-mitotic reagent.Cis-trismethoxy resveratrol inhibits tubulin polymerization with an IC₅₀ value of 4 μM^[1].

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
B16-F10	IC₅₀	1 μM Compound: 72	Anti cancer activity against mouse B16-F10 cells assessed as cell growth inhibition incubated for 40 hrs by Almar Blue stained fluorescence-based assay Anti cancer activity against mouse B16-F10 cells assessed as cell growth inhibition incubated for 40 hrs by Almar Blue stained fluorescence-based assay	[PMID: 32485531]
BXPC-3	GI₅₀	0.0034 μg/mL Compound: 1d	Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human BxPC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
Caco-2	IC₅₀	0.08 μM Compound: 10	Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation assay Cytotoxicity against human Caco-2 cells after 3 days by [3H]thymidine incorporation assay	[PMID: 20627379]
Caco-2	IC₅₀	0.145 μM Compound: 72	Anti cancer activity against human Caco-2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human Caco-2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
DU-145	GI₅₀	0.0054 μg/mL Compound: 1d	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
HCT-116	IC₅₀	0.22 μM Compound: 8Z	Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay Cytotoxicity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 21215623]
HepG2	IC₅₀	0.473 μM Compound: 72	Anti cancer activity against human HepG2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human HepG2 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
HT-29	IC₅₀	0.04 μM Compound: 10	Cytotoxicity against human HT-29 cells after 3 days by [3H]thymidine incorporation assay Cytotoxicity against human HT-29 cells after 3 days by [3H]thymidine incorporation assay	[PMID: 20627379]
HT-29	IC₅₀	0.115 μM Compound: 72	Anti cancer activity against human HT-29 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay Anti cancer activity against human HT-29 cell assessed as cell growth inhibition incubated for 48 hrs by Brdu assay	[PMID: 32485531]
HT-29	IC₅₀	54 nM Compound: 17	Antiproliferative activity against human HT29 cell line by methylene blue dye assay Antiproliferative activity against human HT29 cell line by methylene blue dye assay	[PMID: 17034147]
IMR-90	IC₅₀	0.23 μM Compound: 8Z	Cytotoxicity against human IMR90 cells after 24 hrs by MTT assay Cytotoxicity against human IMR90 cells after 24 hrs by MTT assay	[PMID: 21215623]
KB	IC₅₀	280 nM Compound: 17	Antiproliferative activity against human KB cell line by methylene blue dye assay Antiproliferative activity against human KB cell line by methylene blue dye assay	[PMID: 17034147]
MCF7	IC₅₀	0.12 μM Compound: 8Z	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 21215623]
MKN-45	IC₅₀	218 nM Compound: 17	Antiproliferative activity against human MKN45 cell line by methylene blue dye assay Antiproliferative activity against human MKN45 cell line by methylene blue dye assay	[PMID: 17034147]
NCI-H460	GI₅₀	0.0028 μg/mL Compound: 1d	Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
NCI-H460	IC₅₀	253 nM Compound: 17	Antiproliferative activity against human H460 cell line by methylene blue dye assay Antiproliferative activity against human H460 cell line by methylene blue dye assay	[PMID: 17034147]
SF-268	GI₅₀	0.0044 μg/mL Compound: 1d	Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay	[PMID: 19719153]
SW480	IC₅₀	0.3 μM Compound: 4	Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 48 hrs Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 48 hrs	[PMID: 20395019]
SW480	IC₅₀	0.3 μM Compound: 4	Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 72 hrs Antiproliferative activity against human SW480 cells assessed as cell viability using propidium iodide staining after 72 hrs	[PMID: 20395019]
TSGH 9201	IC₅₀	324 nM Compound: 17	Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay Antiproliferative activity against human TSGH stomach carcinoma cell line by methylene blue dye assay	[PMID: 17034147]

分子量

270.32

Formula

C₁₇H₁₈O₃

CAS 号

94608-23-8

性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, protect from light, 2 years

纯度 & 产品资料

纯度: ≥98.0%

选择批次：

Data Sheet (525 KB) SDS (393 KB)

COA (197 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Schneider Y, et al. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. Int J Cancer. 2003 Nov 1;107(2):189-96. [Content Brief]

cis-Trismethoxy resveratrol 相关分类

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稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量		浓度		体积		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)	×	体积 _(start)	=	浓度 _(final)	×	体积 _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

cis-Trismethoxy resveratrol94608-23-8(Z)-3,5,4'-TrimethoxystilbeneMicrotubule/TubulinInhibitorinhibitorinhibit

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cis-Trismethoxy resveratrol (Synonyms: (Z)-3,5,4'-Trimethoxystilbene)

cis-Trismethoxy resveratrol 相关抗体

cis-Trismethoxy resveratrol 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

纯度 & 产品资料

参考文献

cis-Trismethoxy resveratrol 相关分类

摩尔计算器

稀释计算器

The molarity calculator equation

The dilution calculator equation

Keywords:

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