2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Cisapride monohydrate

Cisapride monohydrate  (Synonyms: 西沙比利一水合物; R 51619 monohydrate; (±)-Cisaprid monohydrate)

目录号: HY-14149A
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Cisapride monohydrate 是一种口服有效的 5-HT4 受体激动剂和 hERG 抑制剂。Cisapride monohydrate 是一种促动力剂，促进或恢复整个胃肠道的运动。Cisapride monohydrate 通过肠肌间神经丛中节后神经末梢释放乙酰胆碱的间接机制刺激胃肠道运动活动。

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Cisapride monohydrate Chemical Structure

Cisapride monohydrate Chemical Structure

CAS No. : 260779-88-2

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Cisapride monohydrate 的其他形式现货产品:

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Cisapride monohydrate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cisapride monohydrate is an orally and potent 5-HT4 receptor agonist and hERG inhibitor. Cisapride monohydrate is an prokinetic agent which facilitates or restores motility throughout the length of the gastrointestinal tract. Cisapride monohydrate stimulates gastrointestinal motor activity through an indirect mechanism involving the release of acetylcholine mediated by postganglionic nerve endings in the myenteric plexus of the gut[1][2].

IC50 & Target

5-HT4 Receptor

0.14 μM (EC50)

Clinical Trial
分子量

483.96

Formula

C23H31ClFN3O5
CAS 号
中文名称

西沙比利一水合物；西沙必利一水合物；普瑞博恩一水合物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cisapride monohydrate 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Cisapride260779-88-2R 51619(±)-Cisaprid西沙比利一水合物西沙必利一水合物普瑞博恩一水合物R51619R-516195-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorhuman ether-a-go-go-related genehERG5-HT4 agonistpatch-clampprokinetic agentgastrointestinalInhibitorinhibitorinhibit

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