2. Protein Tyrosine Kinase/RTK
  3. Src
  4. Cisplatin/Dasatinib prodrug-1

Cisplatin/Dasatinib prodrug-1 

目录号: HY-161687
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Cisplatin/Dasatinib prodrug-1 (Compound 3) 是 Cisplatin (HY-17394) 和 Dasatinib (HY-10181) 的前药。Cisplatin/Dasatinib prodrug-1 对肿瘤细胞系 A2780，MDA-MB-231，MCF7，HCT116，RD，Thp1 和 HL60 具有抗增殖活性，其 IC50 分别为 0.1，0.1，0.36，2.0，0.4，0.3 和 0.25 μM。

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Cisplatin/Dasatinib prodrug-1 Chemical Structure

Cisplatin/Dasatinib prodrug-1 Chemical Structure

CAS No. : 3049801-09-1

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生物活性

Cisplatin/Dasatinib prodrug-1 (Compound 3) is a prodrug of Cisplatin (HY-17394) and Dasatinib (HY-10181). Cisplatin/Dasatinib prodrug-1 exhibits antiproliferative activity against A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1 and HL60 cancer cells with IC50s of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3 and 0.25 μM, respectively[1].

分子量

994.25

Formula

C33H42Cl3N9O6PtS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cisplatin/Dasatinib prodrug-1 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Cisplatin/Dasatinib prodrug-13049801-09-1SrcCisplatinDasatinibprodrugA2780MDA-MB-231MCF7HCT116RDThp1HL60MRC5pd30Inhibitorinhibitorinhibit

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