1. Protein Tyrosine Kinase/RTK
  2. Src
  3. Cisplatin/Dasatinib prodrug-1

Cisplatin/Dasatinib prodrug-1 

目录号: HY-161687
产品使用指南

Cisplatin/Dasatinib prodrug-1 (Compound 3) 是 Cisplatin (HY-17394) 和 Dasatinib (HY-10181) 的前药。Cisplatin/Dasatinib prodrug-1 对肿瘤细胞系 A2780,MDA-MB-231,MCF7,HCT116,RD,Thp1 和 HL60 具有抗增殖活性,其 IC50 分别为 0.1,0.1,0.36,2.0,0.4,0.3 和 0.25 μM。

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Cisplatin/Dasatinib prodrug-1 Chemical Structure

Cisplatin/Dasatinib prodrug-1 Chemical Structure

CAS No. : 3049801-09-1

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生物活性

Cisplatin/Dasatinib prodrug-1 (Compound 3) is a prodrug of Cisplatin (HY-17394) and Dasatinib (HY-10181). Cisplatin/Dasatinib prodrug-1 exhibits antiproliferative activity against A2780, MDA-MB-231, MCF7, HCT116, RD, Thp1 and HL60 cancer cells with IC50s of 0.1, 0.1, 0.36, 2.0, 0.4, 0.3 and 0.25 μM, respectively[1].

分子量

994.25

Formula

C33H42Cl3N9O6PtS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Cisplatin/Dasatinib prodrug-1 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cisplatin/Dasatinib prodrug-1
目录号:
HY-161687
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