2. Anti-infection
  3. Enterovirus
  4. Citrullinated LL-37 4cit

Citrullinated LL-37 3cit 是一种瓜氨酸化 LL-37 (HY-P1222) 肽。Citrullinated LL-37 3cit 在 10 μg/mL 时缺乏抗病毒活性，在 30 μg/mL 时对 HRV 仍有一定活性。Citrullinated LL-37 3cit 降低了 LL-37 的免疫调节活性。Citrullinated LL-37 3cit 显示出降低 HRV 诱导的 CCL5 分泌能力的中度丧失。

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Custom Peptide Synthesis

Citrullinated LL-37 4cit Chemical Structure

Citrullinated LL-37 4cit Chemical Structure

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Citrullinated LL-37 4cit 相关抗体

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  • 生物活性

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生物活性

Citrullinated LL-37 3cit is a citrullinated LL-37 (HY-P1222) peptide. Citrullinated LL-37 3cit lacks all antiviral activity at 10 μg/mL and retains some activity against HRV at 30 μg/mL. Citrullinated LL-37 3cit reduces the immunomodulatory activity of LL-37. Citrullinated LL-37 3cit shows a moderate loss in the ability to reduce HRV-induced CCL5 secretion[1].

IC50 & Target

Human rhinovirus[1]
分子量

4497.20

Formula

C205H336N56O57
Sequence

Leu-Leu-Gly-Asp-Phe-Phe-{Cit}-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-{Cit}-Ile-Val-Gln-{Cit}-Ile-Lys-Asp-Phe-Leu-{Cit}-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
Sequence Shortening

LLGDFF-{Cit}-KSKEKIGKEFK-{Cit}-IVQ-{Cit}-IKDFL-{Cit}-NLVPRTES
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Citrullinated LL-37 4cit 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Citrullinated LL-37 4citEnterovirusRhinovirusHRVHRVsHEVHEVshuman rhinovirusWI-38IL-8CCL5IL-6S. aureusInhibitorinhibitorinhibit

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