2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. CJ-13,610 hydrochloride

CJ-13,610 (hydrochloride) 是具有口服活性，强效的非还原型 5-lipoxygenase 抑制剂，其 IC50 值为 0.07 μM。CJ-13,610 (hydrochloride) 在一个调节性的 LOOH 结合位点上与活化的 LOOH 高亲和力竞争，从而防止 5-lipoxygenase 的催化。CJ-13,610 (hydrochloride) 有望用于研究与 5-lipoxygenase 水平升高相关的疾病，例如炎症反应、过敏性哮喘、各种类型的癌症和动脉粥样硬化。

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CJ-13,610 hydrochloride Chemical Structure

CJ-13,610 hydrochloride Chemical Structure

CAS No. : 179420-27-0

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CJ-13,610 hydrochloride 的其他形式现货产品:

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CJ-13,610 hydrochloride 相关抗体

Top Publications Citing Use of Products

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CJ-13,610 (hydrochloride) is an orally active and potent nonredox-type 5-lipoxygenase inhibitor with an IC50 value of 0.07 μM. CJ-13,610 (hydrochloride) competes with activating LOOH at a regulatory LOOH-binding site with high affinity, thereby preventing 5-lipoxygenase catalysis. CJ-13,610 (hydrochloride) is promising for research of diseases related to elevated levels of 5-lipoxygenase such as inflammatory reactions, allergic asthma, various types of cancer and atherosclerosis[1].

分子量

429.96

Formula

C22H24ClN3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CJ-13,610 hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

CJ-13,610179420-27-0LipoxygenaseLOXorally active5-lipoxygenaseLOOHinflammatory reactionsallergic asthmavarious types of canceratherosclerosisInhibitorinhibitorinhibit

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