1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. Lipoxygenase Inhibitors

Lipoxygenase Inhibitors

5-LOX

12-LOX

15-LOX

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Lipoxygenase Inhibitors, Antagonists & Modulators
Product Name 5-LOX 12-LOX 15-LOX Purity
U-73122
5-LOX
    99.79%
Zileuton
5-LOX
    99.86%
Caffeic acid
5-LO
    99.38%
Wedelolactone
5-LOX, IC50: 2.5 μM
    99.91%
Nordihydroguaiaretic acid
5-LOX, IC50: 8 μM
    99.93%
ML355  
12-LOX, IC50: 0.34 μM
  98.11%
Psoralidin
5-LOX
    99.90%
Indirubin-3'-monoxime
5-LOX, IC50: 7.8-10 μM
    99.89%
Pectolinarigenin
5-LOX
    99.59%
Licofelone
5-LOX, IC50: 0.18 μM
    ≥99.0%
Osavampator
5-LO
    99.89%
β-Boswellic acid
5-LO
    99.89%
15-LOX-1 inhibitor 1    
15-LOX-1, IC50: 0.19 μM
98.60%
11-​Keto-​beta-​boswellic acid
5-LOX
    99.96%
Cirsiliol
5-Lipoxygenase
    99.26%
Malotilate
5-Lipoxygenase, IC50: 4.7 μM
    99.65%
PF-4191834
5-LOX
    99.77%
S-(+)-Marmesin
5-LOX
    99.04%
Docebenone
5-LO
    99.31%
5-O-Demethylnobiletin
5-LOX, IC50: 0.1 μM
    99.91%
Zileuton sodium
5-Lipoxygenase
    98.61%
Timosaponin A1
5-Lipoxygenase, IC50: 3.29 μM
    99.24%
2,5-Di-tert-butylhydroquinone
5-LO, IC50: 1.8 μM
    99.90%
Lonapalene
5-LO
    99.45%
BW 755C
5-LO, IC50: 5 μM
   
3-O-Acetyl-11-hydroxy-beta-boswellic acid
5-LOX
    98.98%
RWJ 63556
5-Lipoxygenase
    99.35%
(E)-KME-4
5-Lipoxygenase, IC50: 1.05 μM
    99.51%
Tebufelone
5-LO
    99.52%
Damnacanthol    
15-LOX
99.76%
Canniprene
5-LO, IC50: 0.4 μM
    ≥98.0%
5-LOX-IN-2
5-LOX, IC50: 0.33 μM
    98.75%
Phenethyl ferulate
5-LOX, IC50: 5.75 μM
    99.88%
Picrinine
5-Lipoxygenase
    99.33%
5-LOX-IN-4
5-Lipoxygenase
    98.07%
Enazadrem
5-Lipoxygenase
   
COX-2/5-LOX-IN-3
5-LOX, IC50: 4.33 μM
   
Lipoxygenin
5-LO, IC50: 5 μM
   
EP6
5-Lipoxygenase, IC50: 0.05 μM
   
Lycopodine
5-Lipoxygenase
   
β-Boswellic acid (Standard)
5-LO
   
Caffeoylcalleryanin    
15-LOX, IC50: 1.59 μM
Linetastine
5-Lipoxygenase
   
mPGES-1/5-LOX-IN-1
5-LOX, IC50: 1.89 μM
   
Atreleuton
5-LO
   
5-LO/mPGES1-IN-1
5-LOX, IC50: 0.4 μM
   
15-LOX-IN-1    
15-LOX, IC50: 1.92 μM
5-LOX-IN-6
5-LO
   
L 670630
5-Lipoxygenase, IC50: 23 nM
   
COX-2/15-LOX-IN-1    
15-LOX, IC50: 2.98 μM
ZLJ-6
5-LOX, IC50: 0.99 μM
   
BF389
5-LOX
   
LY 178002
5-LPO, IC50: 0.6 μM
   
S-2474
5-LO
   
CBS-1114 hydrochloride
5-Lipoxygenase
   
ICI 211965
5-LPO
   
A-69412
5-LO
   
CMI977
5-LO
   
COX/5-LO-IN-1
5-LO, IC50: 2 μM
   
CMI-392
5-LO, IC50: 100 nM
   
AZD 4407
5-Lipoxygenase
   
Bunaprolast
5-LO
   
LP117
5-LO, IC50: 1.1 μM