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  3. CK-3197

CK-3197 是一种较弱的 Peak lll环磷酸腺苷酰化酶抑制剂 (CAMP PDEl)。CK-3197 在体内具有血流动力学和心肌能量效应。CK-3197 是一种咪唑啉衍生物,用作选择性的正性肌力药物用于充血性心力衰竭。CK-3197 带来的正性肌力效应与心率 (HR) 的微小增加有关,并不会对冠状血流 (CBF) 产生不良影响。

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CK-3197 Chemical Structure

CK-3197 Chemical Structure

CAS No. : 132523-92-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CK-3197 is a weaker inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase (CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure. The positive inotropy with CK-3197 is associated with small increases in heart rate (HR) without adverse effects on CBF[1].

分子量

402.45

Formula

C23H22N4O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

CK-3197 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CK-3197
目录号:
HY-117715
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