2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Cl-HIBO

Cl-HIBO 是一种高度亚型选择性 GluR1/2 激动剂 (EC50 分别为 4.7 和 1.7 μM)。Cl-HIBO 是一种有效的 AMPA 受体激动剂 (IC50=0.22 μM)。Cl-HIBO 具有脱敏特性。

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Cl-HIBO Chemical Structure

Cl-HIBO Chemical Structure

CAS No. : 909400-43-7

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Cl-HIBO 相关抗体

Top Publications Citing Use of Products

查看 iGluR 亚型特异性产品:

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AMPA Receptor NMDA Receptor Kainate Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cl-HIBO is a highly subtype-selective GluR1/2 agonist (EC50=4.7 and 1.7 μM, respectively). Cl-HIBO is a potent AMPA receptor agonist (IC50=0.22 μM). Cl-HIBO has desensitizing properties[1].

IC50 & Target

EC50: 4.7, 1.7, 2700 and 1300 μM=GluR1/2/3/4[1]
体外研究
(In Vitro)

Cl-HIBO is a strongly desensitizing full agonist at GluR1[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cl-HIBO 相关抗体:
分子量

206.58

Formula

C6H7ClN2O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cl-HIBO 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cl-HIBO909400-43-7iGluRIonotropic glutamate receptorssubtypeselectivedesensitizingneurotoxicityInhibitorinhibitorinhibit

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产品名称：
Cl-HIBO
目录号：
HY-103229
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