2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. Cloprostenol isopropyl ester

Cloprostenol isopropyl ester 是一种前列腺素 F2α 类似物，是 (+)-Cloprostenol (HY-107381) 的中间体。Cloprostenol isopropyl ester 是一种 FP 受体激动剂，其 Ki 值为 28 nM。

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Cloprostenol isopropyl ester Chemical Structure

Cloprostenol isopropyl ester Chemical Structure

CAS No. : 157283-66-4

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Cloprostenol isopropyl ester 相关抗体

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cloprostenol isopropyl ester, a prostaglandin F2α analogs, is the intermediate of (+)-Cloprostenol (HY-107381). Cloprostenol isopropyl ester is a FP receptor agonist with a Ki value of 28 nM[1][2].

IC50 & Target

FP

 

体内研究
(In Vivo)

Cloprostenol isopropyl ester (25 μg/kg; i.p.; daily, for 4 weeks; male mice) induces changes in the evolution of the spermatogenesis and spermiogenesis[1].
Cloprostenol isopropyl ester (1 μg, 30 μL; injected into the eye; for 2, 4 and 6 h) causes pupil constriction in the cat. Cloprostenol isopropyl ester has an efficacious ocular hypotensive in the lasered monkey[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male mice (50–80 days)[1]
Dosage: 25 μg/kg
Administration: Intraperitoneal injection; daily, for 4 weeks
Result: Stimulated the androgen synthesis in a time-dependent manner.
分子量

466.99

Formula

C25H35ClO6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cloprostenol isopropyl ester 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Cloprostenol isopropyl ester157283-66-4Prostaglandin Receptorprostaglandin F2α analogs(+)-Cloprostenolpupil constrictionocular hypotensiveInhibitorinhibitorinhibit

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产品名称：
Cloprostenol isopropyl ester
目录号：
HY-100571
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