1. 诱导疾病模型产品 Immunology/Inflammation
  2. 免疫与炎症疾病模型 Toll-like Receptor (TLR)
  3. 关节炎模型 心肌炎模型
  4. Complete Freund's adjuvant (CFA, 1 mg/ml)

Complete Freund's adjuvant (CFA, 1 mg/ml) 

目录号: HY-153808B
COA 产品使用指南

Complete Freund's adjuvant (CFA, 1 mg/ml) 是一种与抗原乳化的免疫佐剂,可以增强动物对抗原的免疫反应。Complete Freund's adjuvant (CFA, 1 mg/ml) 也是 Th1 型免疫反应的诱导剂和 TLR 配体。Complete Freund's adjuvant (CFA, 1 mg/ml) 含有热灭活的非活性化结核杆菌,由石蜡油包水乳剂组成。Complete Freund's adjuvant (CFA, 1 mg/ml) 可刺激强烈而持久的免疫反应,可用于诱导大鼠类风湿性关节炎等。

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Complete Freund's adjuvant (CFA, 1 mg/ml) Chemical Structure

Complete Freund's adjuvant (CFA, 1 mg/ml) Chemical Structure

CAS No. : 9007-81-2

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10 mL ¥1125
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Complete Freund's adjuvant (CFA, 1 mg/ml) is an immunoadjuvant emulsified with antigen that can enhance an animal's immune response to an antigen. Complete Freund's adjuvant (CFA, 1 mg/ml) is also an inducer of the Th1 immune response and a ligand of TLRs. Complete Freund's adjuvant (CFA, 1 mg/ml) contains heat-killed inactive tuberculosis bacilli and consists of a paraffin oil-in-water emulsion. Complete Freund's adjuvant (CFA, 1 mg/ml) stimulates a strong and durable immune response and can be used to induce rheumatoid arthritis in rats, and more[1][2][3].

体内研究
(In Vivo)

Complete Freund's adjuvant (1 mg/ml, 0.1 mL;皮下注射;每天一次,持续两天) 可用于诱导 Sprague-Dawley 大鼠类风湿性关节炎。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley rats[3]
Dosage: 1 mg/ml, 0.1 mL
Administration: s.c.; once a day for two days
Result: Increased the index of thymus and spleen.
Decreased the activities of GSH, CAT, SOD and MPO.
Increased the level of IL-1β, IL-6, IL-17, MCP-1, TNF-α, COX-2, 5-LOX, NF-p65, IgG1 and IgG2a.
Reduced level of IL-10.
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Complete Freund's adjuvant (CFA, 1 mg/ml)
目录号:
HY-153808B
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