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CPF-7  (Synonyms: Caerulein precursor fragment)

目录号: HY-P5291
产品使用指南

摩尔计算器

CPF-7 (Caerulein precursor fragment) 是一种胰岛素释放肽，可刺激胰岛素的释放。CPF-7 可CPF-7 可通过上调 PANC-1 导管细胞中 Snai1 的表达来诱导上皮间质转化。CPF-7 还可通过上调 Ngn3 表达来诱导外分泌可塑性。 CPF-7 可用于 2 型糖尿病的研究。

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Custom Peptide Synthesis

CPF-7 Chemical Structure

CPF-7 Chemical Structure

CAS No. : 103238-06-8

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规格 是否有货
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250 mg   询价  

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CPF-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CPF-7 (Caerulein precursor fragment) is an insulin-releasing peptide that stimulates the release of insulin. CPF-7 can induce epithelial-mesenchymal transition by upregulating Snai1 expression in PANC-1 ductal cells. CPF-7 also induces exocrine plasticity by upregulating Ngn3 expression. CPF-7 can be used in the research of type 2 diabetes[1][2].

体外研究
(In Vitro)

CPF-7 (50 nM; 7 days) 将 PANC-1 外分泌细胞转化为胰腺内分泌前体细胞[1]。
CPF-7 (3 µM; 20 min) 刺激 BRIN-BD11 大鼠克隆 β 细胞系中的胰岛素释放[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CPF-7 相关抗体:

Real Time qPCR[1]

Cell Line: PANC1 cells
Concentration: 50 nM
Incubation Time: 7 days (change medium every 24 h)
Result: Increased Ngn3 (the principal determinant of endocrine precursor cells) expression level.

Immunofluorescence[2]

Cell Line: BRIN-BD11 rat clonal β-cells
Concentration: 3 µM
Incubation Time: 20 min
Result: Stimulated insulin release.
分子量

2586.00

Formula

C118H193N33O32
CAS 号
Sequence

Gly-Phe-Gly-Ser-Phe-Leu-Gly-Lys-Ala-Leu-Lys-Ala-Ala-Leu-Lys-Ile-Gly-Ala-Asn-Ala-Leu-Gly-Gly-Ala-Pro-Gln-Gln
Sequence Shortening

GFGSFLGKALKAALKIGANALGGAPQQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CPF-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CPF-7103238-06-8Caerulein precursor fragmentCPF7CPF 7OthersPANC1 cellsNgn3Snai1type 2 diabetesBRIN-BD11 cellsInhibitorinhibitorinhibit

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