2. Apoptosis Autophagy
  3. Apoptosis Autophagy
  4. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2

[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 

目录号: HY-158117
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[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 (Compound 3) 是一种铜络合物，可抑制 HCT116、HCT116DoxR、A2780 和成纤维细胞的细胞活力，IC50 分别为 0.13，0.15，0.66 和 6.24 μM。[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 诱导细胞凋亡 (apoptosis) 和自噬 (autophagy)，在 G0/G1 组织细胞周期。[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 具有抗转移活性。

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[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 Chemical Structure

[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 Chemical Structure

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[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 相关抗体

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生物活性

[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 (Compound 3) is a copper complex, which inhibits cell viability of HCT116, HCT116DoxR, A2780 and fibroblasts, with IC50s of 0.13, 0.15, 0.66 and 6.24 μM, respectively. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 induces apoptosis and autophagy, and arrests cell cycle at G0/G1 phase in HCT116DoxR. [Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 exhibits antimetastatic efficacy[1].

分子量

1266.82

Formula

C52H38Cl2Cu2F12N6O2P22-
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

[Cu2Cl2(4'-(4-Methoxy-1-naphthyl)-terpy)2](PF6)2ApoptosisAutophagycolorectal carcinomaovarian carcinomaHCT116HCT116DoxRA2780Inhibitorinhibitorinhibit

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