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Cyclotriazadisulfonamide hydrochloride  (Synonyms: CADA hydrochloride)

目录号: HY-134809A
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Cyclotriazadisulfonamide hydrochloride (CADA hydrochloride)是一种特定的CD4靶向HIV入侵抑制剂，具有抑制HIV-1复制的活性。Cyclotriazadisulfonamide hydrochloride能够特异性下调人类细胞表面CD4受体的表达。Cyclotriazadisulfonamide hydrochloride在树突状细胞中有效地抑制HIV传播，并对多种HIV-1亚型具有活性。Cyclotriazadisulfonamide hydrochloride在模拟人T细胞的实验中显示出对HIV-1(NL4.3)和SIV(mac251)的防护效果。Cyclotriazadisulfonamide hydrochloride与纤维素醋酸酯（CAP）联合使用时能够产生协同抑制HIV和SIV感染的效果。Cyclotriazadisulfonamide hydrochloride作为微生物凝胶制剂，能够保持CD4下调和抗病毒活性，显示出其作为广谱抗HIV微生物化合物候选的潜力。

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Cyclotriazadisulfonamide hydrochloride Chemical Structure

Cyclotriazadisulfonamide hydrochloride Chemical Structure

CAS No. : 392287-03-5

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Cyclotriazadisulfonamide hydrochloride 的其他形式现货产品:

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Cyclotriazadisulfonamide hydrochloride 相关抗体

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生物活性

Cyclotriazadisulfonamide hydrochloride (CADA hydrochloride) is a specific CD4-targeted HIV entry inhibitor with activity against HIV-1 replication. Cyclotriazadisulfonamide hydrochloride can specifically downregulate the expression of CD4 receptors on the surface of human cells. Cyclotriazadisulfonamide hydrochloride effectively inhibits HIV transmission in dendritic cells and is active against multiple HIV-1 subtypes. Cyclotriazadisulfonamide hydrochloride has shown protective effects against HIV-1 (NL4.3) and SIV (mac251) in experiments simulating human T cells. Cyclotriazadisulfonamide hydrochloride can produce synergistic inhibition of HIV and SIV infection when used in combination with cellulose acetate (CAP). Cyclotriazadisulfonamide hydrochloride as a microbial gel formulation can maintain CD4 downregulation and antiviral activity, showing its potential as a candidate for a broad-spectrum anti-HIV microbial compound[1].

分子量

618.25

Formula

C31H40ClN3O4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
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Cyclotriazadisulfonamide hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Cyclotriazadisulfonamide392287-03-5CADAOthersInhibitorinhibitorinhibit

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