2. Immunology/Inflammation
  3. Cyclophilin
  4. CypD-IN-3

CypD-IN-3 是一种有效的亚型选择性亲环蛋白 D (CypD) 抑制剂。CypD-IN-3 具有亲环蛋白 D (CypD) 亲和力，IC50 值为 0.01 μM。CypD-IN-3 可用于多种疾病的研究，如氧化应激、神经退行性疾病、肝病、衰老、自噬和糖尿病。

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CypD-IN-3 Chemical Structure

CypD-IN-3 Chemical Structure

CAS No. : 2651994-75-9

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CypD-IN-3 相关抗体

Top Publications Citing Use of Products

查看 Cyclophilin 亚型特异性产品:

查看所有亚型
Cyclophilin A Cyclophilin B Cyclophilin C Cyclophilin D Cyclophilin G Cyclophilin E

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1].

IC50 & Target

Cyclophilin D

0.01 μM (IC50)

Cyclophilin A

1.1 μM (IC50)

Cyclophilin B

0.21 μM (IC50)

Cyclophilin E

0.31 μM (IC50)

体外研究
(In Vitro)

CypD-IN-3 (B52) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50 values of 0.01 μM, 1.1 μM, 0.21 μM and 0.31 μM, respectively[1].
CypD-IN-3 (10 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CypD-IN-3 相关抗体:
分子量

972.09

Formula

C53H61N7O11
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CypD-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CypD-IN-32651994-75-9Cyclophilincyclophilin D (CypD)CypACypBCypEoxidative stressischemia-reperfusion injury (IRI)neurodegenerative disordersliver diseasesagingautophagydiabetesInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-151487
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