2. Metabolic Enzyme/Protease Apoptosis
  3. Phosphatase Apoptosis
  4. Cytostatin

Cytostatin 是一种有效的、选择性的蛋白磷酸酶 2A (PP2A) 抑制剂，IC50 值为 210 nM。Cytostatin 具有抗转移特性和良好的抗肿瘤活性，并能诱导细胞凋亡 (apoptosis)。Cytostatin 还能阻止 B16 黑色素瘤细胞与细胞外基质 (层粘连蛋白和胶原蛋白) 成分的粘附。Cytostatin 属于天然产物 fosriecin 家族。

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Cytostatin Chemical Structure

Cytostatin Chemical Structure

CAS No. : 682329-63-1

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Other Forms of Cytostatin:

Cytostatin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cytostatin is an effective and selective protein phosphatase 2A (PP2A) inhibitor with an IC50 value of 210 nM. Cytostatin exhibits anti-metastatic properties, good antitumor activity, and can induce apoptosis. Cytostatin can also prevent the adhesion of B16 melanoma cells to components of the extracellular matrix (laminin and collagen). Cytostatin belongs to the family of natural product fosriecin[1][2][3][4].

IC50 & Target

PP2A[1]
分子量

428.46

Formula

C21H33O7P
CAS 号
结构分类
初始来源

fostriecin
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cytostatin 相关分类

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cytostatin682329-63-1PhosphataseApoptosisPP2Aantitumornatural productsB16 melanoma cellsapoptosisInhibitorinhibitorinhibit

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