1. GPCR/G Protein PI3K/Akt/mTOR
  2. GLP Receptor Akt
  3. d-GLP-2 E33A

d-GLP-2 E33A 是胰高血糖素样肽 2 受体 (GLP-2R) 的激动剂,EC50 为 414 nM。d-GLP-2 E33A 能激活 GLP-2R 和提高 AKT 的磷酸化水平,对 GLP-1R 无刺激作用。d-GLP-2 E33A 可用于肠道吸收不良和炎症性肠病等疾病的研究。

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Custom Peptide Synthesis

d-GLP-2 E33A Chemical Structure

d-GLP-2 E33A Chemical Structure

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查看 Akt 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

d-GLP-2 E33A is an agonist for the glucagon-like peptide 2 receptor (GLP-2R) with an EC50 of 414 nM. d-GLP-2 E33A can activate GLP-2R and increase the phosphorylation of AKT, but has no stimulative effect on GLP-1R. d-GLP-2 E33A can be used in the study of diseases such as intestinal malabsorption and inflammatory bowel diseases[1].

IC50 & Target

EC50: 414 nM (GLP-2R)[1]

分子量

3685.26

Formula

C170H263N47O43S

Sequence

Ac-Ile-Lys-Ala-Gln-Trp-Leu-Ala-Ala-Glu-Phe-Ile-Gln-Ala-Val-Ala-Ala-Val-Leu-Ala-Met-Leu-Arg-Asn-Asn-Gln-Phe-Glu-Phe-Ala-Gly-Val-Ala-His-NH-NH2

Sequence Shortening

Ac-IKAQWLAAEFIQAVAAVLAMLRNNQFEFAGVAH-NH-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
d-GLP-2 E33A
目录号:
HY-P10842
需求量: