2. Neuronal Signaling
  3. Glucosylceramide Synthase (GCS)
  4. D-threo-PPMP hydrochloride

D-threo-PPMP hydrochloride 

目录号: HY-116535 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

D-threo-PPMP hydrochloride 是一种有效的葡萄糖神经酰胺 (GlcCer) 合酶的抑制剂。D-threo-PPMP hydrochloride 可以阻断核分裂，减少囊肿的产生。

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D-threo-PPMP hydrochloride Chemical Structure

D-threo-PPMP hydrochloride Chemical Structure

CAS No. : 139889-65-9

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规格 价格 是否有货 数量
1 mg ￥3500
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Other Forms of D-threo-PPMP hydrochloride:

D-threo-PPMP hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

D-threo-PPMP hydrochloride is a potent inhibitor of glucosylceramide (GlcCer) synthase. D-threo-PPMP hydrochloride can block karyokinesis and reduce cyst production[1][2].

IC50 & Target

glucosylceramide synthase[1]
体外研究
(In Vitro)

D-threo-PPMP (10 μM; 72 h) hydrochloride decreases the MDR1 expression by 70% in KB-V0.01 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

D-threo-PPMP hydrochloride 相关抗体:
分子量

511.18

Formula

C29H51ClN2O3
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥98.0%

COA (164 KB)

产品使用指南 (1538 KB)
参考文献

D-threo-PPMP hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-threo-PPMP139889-65-9Glucosylceramide Synthase (GCS)glucosylceramideGlcCersynthasekaryokinesiscystInhibitorinhibitorinhibit

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