1. Metabolic Enzyme/Protease Apoptosis
  2. NAMPT Apoptosis
  3. (E/Z)-Daporinad hydrochloride

(E/Z)-Daporinad hydrochloride  (Synonyms: (E/Z)-达珀利奈盐酸盐; (E/Z)-FK866 hydrochloride; (E/Z)-APO866 hydrochloride)

目录号: HY-110319
产品使用指南

(E/Z)-Daporinad hydrochloride ((E/Z)-FK866 hydrochloride) 是一种烟酰胺磷酸核糖转移酶 (NAMPT) 的强效抑制剂。(E/Z)-Daporinad hydrochloride 通过特异性抑制 NAMPT 逐渐耗尽细胞内的 NAD+,从而诱导细胞凋亡 (apoptosis)。(E/Z)-Daporinad hydrochloride 可用于癌症生物学和炎症性疾病的研究。

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(E/Z)-Daporinad hydrochloride Chemical Structure

(E/Z)-Daporinad hydrochloride Chemical Structure

CAS No. : 1785666-54-7

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  • 参考文献

生物活性

(E/Z)-Daporinad hydrochloride ((E/Z)-FK866 hydrochloride) is a potent inhibitor of nicotinamide phosphoribose transferase (NAMPT). (E/Z)-Daporinad hydrochloride induces apoptosis by specifically inhibiting NAMPT to gradually deplete intracellular NAD+. (E/Z)-Daporinad hydrochloride can be used in the study of cancer biology and inflammatory diseases[1].

分子量

427.97

Formula

C24H30ClN3O2

CAS 号
中文名称

(E/Z)-达珀利奈盐酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(E/Z)-Daporinad hydrochloride
目录号:
HY-110319
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