2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. DBCO-PEG3-Glu-Val-Cit-PABC-MMAE

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 

目录号: HY-164309
产品使用指南

摩尔计算器

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 是 ADC 的药物-Linker 缀合物。DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 含有强效微管蛋白抑制剂 Monomethyl auristatin E (MMAE, HY-15162)，可用于合成双药 ADC。

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DBCO-PEG3-Glu-Val-Cit-PABC-MMAE Chemical Structure

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE Chemical Structure

CAS No. : 2861998-23-2

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DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 相关抗体

Top Publications Citing Use of Products

查看 Drug-Linker Conjugates for ADC 亚型特异性产品:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. DBCO-PEG3-Glu-Val-Cit-PABC-MMAE contains a potent tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162) and can be used for synthesis of dual-drug ADC[1].

体外研究
(In Vitro)

ADC 由一种抗体组成，ADC 细胞毒素通过 ADC 接头连接到该抗体上。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 相关抗体:
分子量

1729.06

Formula

C90H129N13O21
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DBCO-PEG3-Glu-Val-Cit-PABC-MMAE2861998-23-2Drug-Linker Conjugates for ADCdrug-linker conjugateMMAEdual-drug ADCInhibitorinhibitorinhibit

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