1. Anti-infection
  2. Antibiotic Bacterial Fungal
  3. Defensin HNP-3 human

Defensin HNP-3 human 是具有细胞毒性的抗生素肽,被称为“防御素”。Defensin HNP-3 human 对金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌具有抑制活性。Defensin HNP-3 human 最初合成为 94 个氨基酸 preproHNP(1-94),共翻译蛋白水解为 proHNP(20-94),去除阴离子前体后才转化为成熟的 HNP (65-94)。

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Custom Peptide Synthesis

Defensin HNP-3 human Chemical Structure

Defensin HNP-3 human Chemical Structure

CAS No. : 136661-76-2

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  • 生物活性

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生物活性

Defensin HNP-3 human is a cytotoxic antibiotic peptide known as "defensin". Defensin HNP-3 human has inhibitory activity against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. Defensin HNP-3 human is initially synthesized as the 94 amino acids preproHNP(1-94), which is hydrolyzed to proHNP(20-94) and converted to mature HNP(65-94) after the removal of anion precursors[1][2].

分子量

3486.04

Formula

C151H222N44O40S6

CAS 号
Sequence

Asp-Cys-Tyr-Cys-Arg-Ile-Pro-Ala-Cys-Ile-Ala-Gly-Glu-Arg-Arg-Tyr-Gly-Thr-Cys-Ile-Tyr-Gln-Gly-Arg-Leu-Trp-Ala-Phe-Cys-Cys (Disulfide bridge:Cys2-Cys30,Cys4-Cys19,Cys9-Cys29)

Sequence Shortening

DCYCRIPACIAGERRYGTCIYQGRLWAFCC (Disulfide bridge:Cys2-Cys30,Cys4-Cys19,Cys9-Cys29)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Defensin HNP-3 human
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