1. Metabolic Enzyme/Protease Apoptosis
  2. Endogenous Metabolite Apoptosis
  3. Delta-12-Prostaglandin J2

Delta-12-Prostaglandin J2  (Synonyms: Δ12-PGJ2)

目录号: HY-113505 纯度: ≥99.0%
COA 产品使用指南

Delta-12-Prostaglandin J2 (Δ12-PGJ2) 是一种环戊烯酮前列腺素 (PG),对多种肿瘤细胞的生长具有抗增殖作用。Delta-12-Prostaglandin J2 是前列腺素 D2 的天然脱水产物,能够通过 caspase 激活诱导 HeLa 细胞的凋亡 (apoptosis)。

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Delta-12-Prostaglandin J2 Chemical Structure

Delta-12-Prostaglandin J2 Chemical Structure

CAS No. : 87893-54-7

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100 μg(2.99 mM * 100 μL in Methyl acetate) ¥842
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2].

IC50 & Target

Human Endogenous Metabolite

 

分子量

334.45

Formula

C20H30O4

CAS 号
性状

液体

颜色

Colorless to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Solution, -20°C, 2 years

纯度 & 产品资料

纯度: ≥99.0%

参考文献
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Delta-12-Prostaglandin J2
目录号:
HY-113505
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