2. Metabolic Enzyme/Protease Others
  3. Cytochrome P450 Isotope-Labeled Compounds
  4. Desmethylcitalopram-d4 hydrochloride

Desmethylcitalopram-d4 hydrochloride  (Synonyms: DCIT-d4 hydrochloride)

目录号: HY-113739S1
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摩尔计算器

Desmethylcitalopram-d4 hydrochloride 是氘代标记的 Desmethylcitalopram hydrochloride (HY-113739)。Desmethylcitalopram (DCIT) 是 Citalopram (HY-121203) 的活性代谢物。Desmethylcitalopram 具有抗抑郁作用。Desmethylcitalopram 还抑制细胞色素 P450-2D6、-2C19，IC50s 分别为 39.5 和 53.5 μM。

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Desmethylcitalopram-d<sub>4</sub> hydrochloride Chemical Structure

Desmethylcitalopram-d4 hydrochloride Chemical Structure

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规格 是否有货
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Other Forms of Desmethylcitalopram-d4 hydrochloride:

Desmethylcitalopram-d4 hydrochloride 相关抗体

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查看 Cytochrome P450 亚型特异性产品:

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Desmethylcitalopram-d4 hydrochloride is deuterated labeled Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC50s of 39.5 and 53.5 μM[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Desmethylcitalopram-d4 hydrochloride 相关抗体:
分子量

350.85

Formula

C19H16D4ClFN2O
非标记 CAS

97743-99-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Desmethylcitalopram-d4 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Desmethylcitalopram-d4DCIT-d4Cytochrome P450Isotope-Labeled CompoundsCYPsCitalopramantidepressant2D62C19Inhibitorinhibitorinhibit

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