2. Immunology/Inflammation Apoptosis
  3. COX Apoptosis
  4. Diclofenac diethylamine (Standard)

Diclofenac diethylamine (Standard)  (Synonyms: 双氯芬酸二乙胺 (Standard))

目录号: HY-15036AR 纯度: ≥98%
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摩尔计算器

Diclofenac (diethylamine) (Standard) 是 Diclofenac (diethylamine) 的分析标准品。本产品用于研究及分析应用。Diclofenac diethylamine 是一种有效的，非选择性抗炎剂，为 COX 的抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的 IC50 值分别为 4 和 1.3 nM。Diclofenac diethylamine 对绵羊 COX-1 和 COX-2 的 IC50 值分别为 5.1 μM，0.84 μM。Diclofenac diethylamine 通过活化 caspase 级联反应来诱导神经干细胞凋亡 (apoptosis)。

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Diclofenac diethylamine (Standard) Chemical Structure

Diclofenac diethylamine (Standard) Chemical Structure

CAS No. : 78213-16-8

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生物活性

Diclofenac (diethylamine) (Standard) is the analytical standard of Diclofenac (diethylamine). This product is intended for research and analytical applications. Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

分子量

369.29

Formula

C₁₈H₂₂Cl₂N₂O₂
CAS 号
中文名称

双氯芬酸二乙胺 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Diclofenac diethylamine (Standard) 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Diclofenac diethylamine (Standard)78213-16-8双氯芬酸二乙胺 (Standard)COXApoptosisCyclooxygenaseanti-inflammatoryCOX-1COX-2CHOovineneuralstemcellsNSCscaspasecascadeInhibitorinhibitorinhibit

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