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Diethylumbelliferyl phosphate  (Synonyms: 磷酸二乙基伞形酮; DEUP)

目录号: HY-134451
产品使用指南

Diethylumbelliferyl phosphate (DEUP) 是一种选择性强效胆固醇酯酶抑制剂,它在体外不会抑制蛋白激酶活性 A,并且能通过阻断胆固醇运输到类固醇生成细胞的线粒体中来有效破坏类固醇生成,其 IC50 为 11.6 μM,可能限制膳食胆固醇的吸收。

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Diethylumbelliferyl phosphate Chemical Structure

Diethylumbelliferyl phosphate Chemical Structure

CAS No. : 897-83-6

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Diethylumbelliferyl phosphate (DEUP), a selective and potent inhibitor of cholesterol esterase, does not inhibit protein kinase activity A in vitro, and it effectively disrupts steroidogenesis by blocking the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM, potentially limiting dietary cholesterol absorption.

分子量

312.25

Formula

C14H17O6P

CAS 号
中文名称

磷酸二乙基伞形酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

Diethylumbelliferyl phosphate 相关分类

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产品名称:
Diethylumbelliferyl phosphate
目录号:
HY-134451
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