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  2. Isotope-Labeled Compounds
  3. Dihydrocapsaicin-d3

Dihydrocapsaicin-d3  (Synonyms: 二氢辣椒碱-d3)

目录号: HY-N0361S
产品使用指南

Dihydrocapsaicin-d3 是氘代标记的 Dihydrocapsaicin (HY-N0361)。DiHydrocapsaicin 是一种辣椒素,是一种有效的选择性 TRPV1(瞬时受体电位香草酸通道 1)激动剂。二氢辣椒素可降低 AIFBaxCaspase-3 表达,并增加 Bcl-2Bcl -xLp-Akt 级别。二氢辣椒素通过 PI3K/Akt 调节增强大鼠缺血性中风后低温诱导的神经保护。

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Dihydrocapsaicin-d<sub>3</sub> Chemical Structure

Dihydrocapsaicin-d3 Chemical Structure

CAS No. : 1330261-21-6

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1 mg ¥7600
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Other Forms of Dihydrocapsaicin-d3:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dihydrocapsaicin-d3is the deuterium labeledDihydrocapsaicin(HY-N0361)[1]. Dihydrocapsaicin, a capsaicin, is a potent and selective TRPV1 (transient receptor potential vanilloid channel 1) agonist. Dihydrocapsaicin reduces AIF, Bax, and Caspase-3 expressions, and increased Bcl-2, Bcl-xL and p-Akt levels. Dihydrocapsaicin enhances the hypothermia-induced neuroprotection following ischemic stroke via PI3K/Akt regulation in rat[2][3][4].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

310.45

Formula

C18H26D3NO3

CAS 号
非标记 CAS

19408-84-5

中文名称

二氢辣椒素-d3;二氢辣椒碱-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dihydrocapsaicin-d3
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HY-N0361S
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