1. Metabolic Enzyme/Protease
  2. Dipeptidyl Peptidase Glucosidase Amylases
  3. DPP-4-IN-11

DPP-4-IN-11 (compound 10) 是一种具有口服活性的 DPP-4 抑制剂 (IC50=2.75 μM),具有抗 2 型糖尿病活性。DPP-4-IN-11 通过抑制 α-葡萄糖苷酶 (IC50=3.02 μM) 和 α-淀粉酶 (IC50=3.3 μM) 的活性来发挥降糖作用。

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DPP-4-IN-11 Chemical Structure

DPP-4-IN-11 Chemical Structure

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查看 Dipeptidyl Peptidase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DPP-4-IN-11 (compound 10) is an orally active DPP-4 inhibitor (IC50=2.75 μM) with anti-type 2 diabetes activity. DPP-4-IN-11 exerts its glucose-lowering effect by inhibiting the activities of α-glucosidase (IC50=3.02 μM) and α-amylase (IC50=3.3 μM)[1].

IC50 & Target[1]

DPP-4

2.75 μM (IC50)

分子量

428.53

Formula

C20H20N4O3S2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DPP-4-IN-11
目录号:
HY-159491
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