1. Antibody-drug Conjugate/ADC Related
  2. Radionuclide-Drug Conjugates (RDCs)
  3. DTPA anhydride

DTPA anhydride 是双功能的螯合剂,其酸酐能够与蛋白质中的氨基(如赖氨酸残基)反应,形成稳定的酰胺键。DTPA anhydride 还能够与放射性核素结合,从而合成放射性核素标记的药物偶联物 (RDC)。RDC 具有特定靶向生物分子的能力,可应用于医疗成像或治疗。

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DTPA anhydride Chemical Structure

DTPA anhydride Chemical Structure

CAS No. : 23911-26-4

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查看 Radionuclide-Drug Conjugates (RDCs) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

生物活性

DTPA anhydride is a bifunctional chelator whose anhydride can react with amino groups in proteins (such as lysine residues) to form stable amide bonds. DTPA anhydride can also bind to radionuclides to synthesize radionuclide-labeled drug conjugates (RDCs). RDCs have the ability to specifically target biomolecules and can be used in medical imaging or therapy.

IC50 & Target

RDC Bifunctional Chelator

 

分子量

357.32

Formula

C14H19N3O8

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DTPA anhydride
目录号:
HY-W011118
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