1. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  2. ADC Cytotoxin DNA Alkylator/Crosslinker
  3. Duocarmycin Analog

Duocarmycin Analog 是 Duocarmycin 的类似物,可用作 DNA 烷化剂 (DNA alkylator) 和 抗体偶联活性分子 (ADC cytotoxin) 的毒素部分。

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Duocarmycin Analog Chemical Structure

Duocarmycin Analog Chemical Structure

CAS No. : 372954-15-9

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规格 价格 是否有货 数量
1 mg ¥5800
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Duocarmycin Analog is an analog of Duocarmycin, and used as an DNA alkylator and ADC cytotoxin[1].

IC50 & Target[1]

Duocarmycins

 

DNA alkylator

 

体外研究
(In Vitro)

ADC 细胞毒素(也称为有效载荷)是诱导抗体药物偶联物 (ADC) 中的靶细胞死亡的细胞毒性剂。ADC 是一种由单克隆抗体、连接子和细胞毒素组成的靶向药物。细胞毒素是最重要的成分,因为它决定了 ADC 杀死癌细胞的效力。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

611.09

Formula

C34H31ClN4O5

CAS 号
性状

固体

颜色

Off-white to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Duocarmycin Analog
目录号:
HY-129355
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