1. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  2. RAR/RXR
  3. (E)-XS-060

(E)-XS-060 是 XS-060 的异构体。XS-060 是 RXRα 拮抗剂。XS-060 抑制 pRXRα-PLK1 相互作用。XS-060 诱导 RXRα 依赖性有丝分裂停滞。XS-060 对乳腺癌、肺腺癌和肝癌表现出良好的抗肿瘤活性。

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(E)-XS-060 Chemical Structure

(E)-XS-060 Chemical Structure

CAS No. : 2787626-06-4

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查看 RAR/RXR 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(E)-XS-060 is an isomer of XS-060. XS-060 is a RXRα antagonist. XS-060 inhibits pRXRα-PLK1 interaction. XS-060 induces RXRα-dependent mitotic arrest. XS-060 exhibits good antitumor activity against breast cancer, lung adenocarcinoma, and liver cancer[1].

IC50 & Target[1]

RXR α

 

分子量

334.37

Formula

C20H18N2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(E)-XS-060
目录号:
HY-149085A
需求量: