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  4. E3 ligase Ligand 24

E3 ligase Ligand 24 (Compound 24) 是 E3 连接酶 DCAF15 的有效配体 (IC50= 0.053 μM)。由于其选择性和强大的结合特性，E3 ligase Ligand 24 在靶向蛋白质降解的研究中起着关键作用。

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E3 ligase Ligand 24 Chemical Structure

E3 ligase Ligand 24 Chemical Structure

CAS No. : 3038773-47-3

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E3 ligase Ligand 24 相关抗体

Top Publications Citing Use of Products

  • 生物活性

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生物活性

E3 ligase Ligand 24 (Compound 24) is a Potent Ligand for the E3 Ligase DCAF15 (IC50= 0.053 μM). Due to E3 ligase Ligand 24’s selectivity and potent binding characteristics, it is pivotal in the study of targeted protein degradation[1].

体外研究
(In Vitro)

E3 ligase Ligand 24 (5μM; 24h) 处理 HiBiT 标签的 BRD4 的 HEK293细胞，可以有效降解 BRD4 蛋白，且该降解并非通过 DCAF15 介导。[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

E3 ligase Ligand 24 相关抗体:
分子量

513.39

Formula

C21H22Cl2N4O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

E3 ligase Ligand 24 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E3 ligase Ligand 243038773-47-3OthersPROTAC ComponentDCAF15 TargetingProtein DegradationInhibitorinhibitorinhibit

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