2. Anti-infection
  3. HPV
  4. E6AP-mimicking peptide

E6AP-mimicking peptide (compound 13) 是一种高亲和力、选择性、不可逆且有效的肽基共价 HPV16 E6 抑制剂，使用半胱氨酸反应性丙烯酰胺弹头靶向 16E6 癌蛋白。E6AP-mimicking peptide 的 Ki 为 17 nM。E6AP-mimicking peptide 靶向 E6 结合口袋中出现的所有残基，以破坏 16E6 和 E6AP 的结合界面。E6AP-mimicking peptide 选择性地结合并交联 PBS 或蛋白质混合物中的 MBP-16E6。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

E6AP-mimicking peptide Chemical Structure

E6AP-mimicking peptide Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

E6AP-mimicking peptide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

E6AP-mimicking peptide (compound 13) is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture[1].

分子量

2630.09

Formula

C128H193N31O29
Sequence

{9-fluorenyl acetamido}-Ile-Pro-Gln-Ser-Ala-Glu-Leu-Thr-Leu-Gln-Glu-Leu-{Dha}-Arg-Arg-Lys-Lys-Lys(1-anthracenyl acetamido)-NH2
Sequence Shortening

{9-fluorenyl acetamido}-IPQSAELTLQELL-{Dha}-RRKK-{Lys(1-anthracenyl acetamido)}-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

E6AP-mimicking peptide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

E6AP-mimicking peptideHPVHuman papillomavirusIrreversiblecovalentHPV16 E6cysteine-reactive acrylamide warhead16E6E6APMBP-16E6Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
E6AP-mimicking peptide
目录号：
HY-P10428
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z