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  4. EA-230

EA-230 是一种合成寡肽,最初来源于 β-人绒毛膜促性腺激素 (β-hCG) 裂解物。EA-230 具有抗炎作用,可用于脓毒症的研究。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

EA-230 Chemical Structure

EA-230 Chemical Structure

CAS No. : 503844-09-5

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2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
5 mg ¥650
In-stock
10 mg ¥1000
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

EA-230 is a synthetic oligopeptide originally derived from beta-human chorionic gonadotropin (beta-hCG) lysates. EA-230 has anti-inflammatory effects and can be used for the research of sepsis[1].

体内研究
(In Vivo)

EA-230 (30-50 mg/kg; i.p.; twice daily for four consecutive days) improves survival and attenuate loss of kidney function in a mouse model of renal ischemia/reperfusion injury (IRI) and ischemia-induced delayed graft function after allogenic kidney transplantation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male C57Bl/6 mice, ischemia reperfusion injury model[1]
Dosage: 20, 30, 40 or 50 mg/kg
Administration: Intraperitoneal injection, twice daily for four consecutive days
Result: Improved survival markedly. With doses between 30–50 mg/kg survival reached 56–62%, the low dose treatment with 20 mg/kg did not have a beneficial effect. Significantly increased renal blood flow (RBF), attenuated CTGF up-regulation, enhanced tubular epithelial cell regeneration and attenuated TGF-beta activation.
Clinical Trial
分子量

373.40

Formula

C15H27N5O6

CAS 号
性状

固体

颜色

White to off-white

Sequence Shortening

AQGV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 125 mg/mL (334.76 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.6781 mL 13.3905 mL 26.7809 mL
5 mM 0.5356 mL 2.6781 mL 5.3562 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6781 mL 13.3905 mL 26.7809 mL 66.9523 mL
5 mM 0.5356 mL 2.6781 mL 5.3562 mL 13.3905 mL
10 mM 0.2678 mL 1.3390 mL 2.6781 mL 6.6952 mL
15 mM 0.1785 mL 0.8927 mL 1.7854 mL 4.4635 mL
20 mM 0.1339 mL 0.6695 mL 1.3390 mL 3.3476 mL
25 mM 0.1071 mL 0.5356 mL 1.0712 mL 2.6781 mL
30 mM 0.0893 mL 0.4463 mL 0.8927 mL 2.2317 mL
40 mM 0.0670 mL 0.3348 mL 0.6695 mL 1.6738 mL
50 mM 0.0536 mL 0.2678 mL 0.5356 mL 1.3390 mL
60 mM 0.0446 mL 0.2232 mL 0.4463 mL 1.1159 mL
80 mM 0.0335 mL 0.1674 mL 0.3348 mL 0.8369 mL
100 mM 0.0268 mL 0.1339 mL 0.2678 mL 0.6695 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
EA-230
目录号:
HY-106279
需求量: